MolNFT v1 · #174572 · protein
Crystal structure of rice OS3BGLU7 with glucoimidazole
7BZM · Beta-glucosidase 7: “Crystal structure of rice OS3BGLU7 with glucoimidazole”. X-ray diffraction, 3 ligands (GIM, ZN, SO4), 7 pockets (best druggability 0.70). MolNFT v1 #174572 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7BZM
- Type
- protein
- Length
- 942 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Beta-glucosidase 7
- EC
- 3.2.1.21
- UniProt
- Q75I93
- Ligands
- GIM, ZN, SO4
- Pockets
- 7 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 16% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Beta-glucosidase 7 (EC 3.2.1.21) | protein | 471 | 44% helix, 16% strand | Q75I93 |
Ligands and binding sites
- GIM · Glucoimidazole · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · chains A, B
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 411 | 0.70 | 0.81 | 39 | GIM |
| 2 | 403 | 0.68 | 0.80 | 37 | GIM |
| 3 | 333 | 0.58 | 0.76 | 35 | empty |
| 4 | 311 | 0.55 | 0.75 | 32 | empty |
| 5 | 50 | 0.37 | 0.80 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 617 Ų buried · 5 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q75I93
- Elsewhere: RCSB PDB 7BZM · PDBe 7BZM · UniProt Q75I93
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