MolNFT v1 · #174570 · protein
Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin Y1 complex
7BZK · Ferredoxin-thioredoxin reductase catalytic chain…: “Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin Y1 complex”. X-ray diffraction, 1 ligand (SF4), 1 pocket (best druggability 0.33). MolNFT v1 #174570 on…
- PDB
- 7BZK
- Type
- protein
- Length
- 214 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic; Thioredoxin Y1…
- EC
- 1.8.7.2
- UniProt
- Q9SJ89, Q6NPF9
- Ligands
- SF4
- Pockets
- 1 · best druggability 0.33
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ferredoxin-thioredoxin reductase catalytic chain, chloroplastic (EC 1.8.7.2) | protein | 112 | 50% helix, 6% strand | Q9SJ89 |
| B | Thioredoxin Y1, chloroplastic | protein | 102 | 43% helix, 25% strand | Q6NPF9 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.33 | 0.76 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 852 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 7BZK · Crystal structure of ferredoxin: thioredoxin reductase and thioredoxin y1 complex · the same entry in another collection · chain A against A, TM-score 1.00
- Q9SJ89 · AlphaFold monomer V2.0 prediction for ferredoxin-thioredoxin reductase catalytic chain… · a predicted model of the same protein · chain A against A, TM-score 0.99
- Q6NPF9 · AlphaFold monomer V2.0 prediction for thioredoxin Y1, chloroplastic (Q6NPF9) · a predicted model of the same protein · chain B against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9SJ89
- Every structure of UniProt Q6NPF9
- Elsewhere: RCSB PDB 7BZK · PDBe 7BZK · UniProt Q9SJ89 · UniProt Q6NPF9
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