MolNFT v1 · #174535 · protein
Crystal structure of the legionella pneumophila LEGK7 effector kinase
7BYK: “Crystal structure of the legionella pneumophila LEGK7 effector kinase”. X-ray diffraction, 15 pockets (best druggability 0.80). MolNFT v1 #174535 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7BYK
- Type
- protein
- Length
- 900 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LEGK7
- UniProt
- A0A4T1L9X4
- Pockets
- 15 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 52% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | LEGK7 | protein | 448 | 52% helix, 11% strand | A0A4T1L9X4 |
| B | LEGK7 | protein | 452 | 52% helix, 11% strand | A0A4T1L9X4 |
Pockets
15 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.80 | 0.95 | 37 | empty |
| 2 | 169 | 0.78 | 0.94 | 36 | empty |
| 3 | 379 | 0.72 | 0.84 | 46 | empty |
| 4 | 232 | 0.70 | 0.86 | 29 | empty |
| 5 | 222 | 0.67 | 0.84 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 500 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 7BYK · Crystal structure of the Legionella pneumophila LegK7 effector kinase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A4T1L9X4
- Elsewhere: RCSB PDB 7BYK · PDBe 7BYK · UniProt A0A4T1L9X4
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