MolNFT v1 · #174421 · protein
Eucommia ulmoides TPT3 mutant -C94Y/A95F
7BUW · FPS3: “Eucommia ulmoides TPT3 mutant -C94Y/A95F”. X-ray diffraction, 12 pockets (best druggability 0.79). MolNFT v1 #174421 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7BUW
- Type
- protein
- Length
- 629 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- FPS3
- UniProt
- A0A1L3KPU1
- Pockets
- 12 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 78% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | FPS3 | protein | 314 | 79% helix, 0% strand | A0A1L3KPU1 |
| B | FPS3 | protein | 315 | 77% helix, 0% strand | A0A1L3KPU1 |
Pockets
12 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 142 | 0.79 | 0.96 | 26 | empty |
| 2 | 304 | 0.73 | 0.86 | 34 | empty |
| 3 | 96 | 0.70 | 0.92 | 24 | empty |
| 4 | 415 | 0.62 | 0.77 | 43 | empty |
| 5 | 204 | 0.54 | 0.78 | 30 | empty |
Interfaces
1 interface between chains.
- A–B · 1917 Ų buried · 17 hydrogen bonds · protein-protein
Compared structures
- 7BUW · Eucommia ulmoides TPT3 mutant -C94Y/A95F · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1L3KPU1
- Elsewhere: RCSB PDB 7BUW · PDBe 7BUW · UniProt A0A1L3KPU1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.