MolNFT v1 · #174417 · protein
Chalcone synthase from glycine max (L.) merr (soybean)
7BUS: “Chalcone synthase from glycine max (L.) merr (soybean)”. X-ray diffraction, 6 pockets (best druggability 0.66). MolNFT v1 #174417 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7BUS
- Type
- protein
- Length
- 778 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chalcone synthase
- EC
- 2.3.1.74
- UniProt
- Q6X0M8
- Pockets
- 6 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Chalcone synthase (EC 2.3.1.74) | protein | 389 | 42% helix, 23% strand | Q6X0M8 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 252 | 0.66 | 0.83 | 40 | empty |
| 2 | 273 | 0.66 | 0.82 | 35 | empty |
| 3 | 214 | 0.56 | 0.79 | 37 | empty |
| 4 | 231 | 0.54 | 0.77 | 40 | empty |
| 5 | 55 | 0.46 | 0.84 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 3154 Ų buried · 64 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 modified (nonstandard, oxidation).
Compared structures
- 7BUS · Chalcone synthase from Glycine max (L.) Merr (soybean) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6X0M8
- Elsewhere: RCSB PDB 7BUS · PDBe 7BUS · UniProt Q6X0M8
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