GL1X · GenesisL1 explorer

MolNFT v1 · #174359 · protein

Cryo-EM structure of a human ATP11C-CDC50A flippase in ptdetn-occluded E2-alf state

7BSW: “Cryo-EM structure of a human ATP11C-CDC50A flippase in ptdetn-occluded E2-alf state”. Electron microscopy, 4 ligands (ALF, PEE, NAG). MolNFT v1 #174359 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
7BSW
Type
protein
Length
1,139 residues
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Ligands
ALF, PEE, NAG, MAN

Structure

electron microscopy · 2 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein815——
C—protein324——

Ligands and binding sites

  • ALF · Tetrafluoroaluminate ion · ligand · chains A
  • PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · ligand · chains A
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 4 copies · chains A, C
  • MAN · alpha-D-mannopyranose · sugar

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 7BSW · Cryo-EM structure of a human ATP11C-CDC50A flippase in PtdEtn-occluded E2-AlF state · the same entry in another collection · chain A against A, TM-score 1.00

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