MolNFT v1 · #17435 · protein
4-oxalocrotonate tautomerase-triclinic crystal form
1OTF: “4-oxalocrotonate tautomerase-triclinic crystal form”. X-ray diffraction, 8 pockets (best druggability 0.50). MolNFT v1 #17435 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1OTF
- Type
- protein
- Length
- 354 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 4-oxalocrotonate tautomerase
- EC
- 5.3.2.-
- UniProt
- P49172
- Pockets
- 8 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F | 4-oxalocrotonate tautomerase (EC 5.3.2.-) | protein | 59 | 42% helix, 32% strand | P49172 |
Pockets
8 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 158 | 0.50 | 0.78 | 21 | empty |
| 2 | 102 | 0.49 | 0.81 | 19 | empty |
| 3 | 126 | 0.48 | 0.79 | 18 | empty |
| 4 | 138 | 0.48 | 0.78 | 21 | empty |
| 5 | 107 | 0.45 | 0.78 | 17 | empty |
Interfaces
15 interfaces between chains.
- C–F · 927 Ų buried · 11 hydrogen bonds · protein-protein
- B–E · 923 Ų buried · 9 hydrogen bonds · protein-protein
- A–D · 917 Ų buried · 10 hydrogen bonds · protein-protein
- A–E · 622 Ų buried · 6 hydrogen bonds · protein-protein
- B–F · 608 Ų buried · 6 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P49172
- Elsewhere: RCSB PDB 1OTF · PDBe 1OTF · UniProt P49172
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