MolNFT v1 · #1742 · protein

Glutathione S-transferase yfyf cys 47-carboxymethylated class pi, free enzyme

1BAY · Glutathione S-transferase class pi: “Glutathione S-transferase yfyf cys 47-carboxymethylated class pi, free enzyme”. X-ray diffraction, 1 pocket (best druggability 0.71). MolNFT v1 #1742 on GenesisL1: 3D structure, binding sites and…

PDB: 1BAY
Type: protein
Length: 387 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glutathione S-transferase class pi
EC: 2.5.1.18
UniProt: P19157
Pockets: 1 · best druggability 0.71

Structure

x-ray diffraction · 2 distinct chains · 60% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glutathione S-transferase class pi (EC 2.5.1.18)	protein	193	61% helix, 9% strand	P19157
B	Glutathione S-transferase class pi (EC 2.5.1.18)	protein	194	60% helix, 9% strand	P19157

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	829	0.71	0.76	99	empty

Interfaces

1 interface between chains.

A–B · 954 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

1BAY · Glutathione S-transferase yfyf cys 47-carboxymethylated class pi, free enzyme · the same entry in another collection · chain A against A, TM-score 1.00
P19157 · AlphaFold monomer V2.0 prediction for glutathione S-transferase P 1 (P19157) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19157
Elsewhere: RCSB PDB 1BAY · PDBe 1BAY · UniProt P19157

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