MolNFT v1 · #173993 · protein

Crystal structure of recj-CDC45 from methanothermobacter thermoautotrophicus

7BHI · Conserved protein: “Crystal structure of recj-CDC45 from methanothermobacter thermoautotrophicus”. X-ray diffraction, 1 ligand (MN), 4 pockets (best druggability 0.77). MolNFT v1 #173993 on GenesisL1: 3D structure, binding sites and…

PDB: 7BHI
Type: protein
Length: 884 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved protein
UniProt: O27473
Ligands: MN
Pockets: 4 · best druggability 0.77

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Conserved protein	protein	444	48% helix, 16% strand	O27473
B	Conserved protein	protein	440	48% helix, 16% strand	O27473

Ligands and binding sites

MN · Manganese (II) ion · metal · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1041	0.77	0.79	78	empty
2	767	0.76	0.80	63	empty
3	965	0.74	0.78	74	empty
4	74	0.49	0.83	22	empty

Interfaces

1 interface between chains.

A–B · 443 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

7BHI · Crystal structure of RecJ-Cdc45 from Methanothermobacter Thermoautotrophicus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O27473
Elsewhere: RCSB PDB 7BHI · PDBe 7BHI · UniProt O27473

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