MolNFT v1 · #173991 · protein
Gene-engineered variant of fusionred with TRP based chromophore - 2.1A
7BHG · Fluorescent protein FP480: “Gene-engineered variant of fusionred with TRP based chromophore - 2.1A”. X-ray diffraction, 1 ligand (TUK), 3 pockets (best druggability 0.76). MolNFT v1 #173991 on GenesisL1: 3D structure, binding sites…
- PDB
- 7BHG
- Type
- protein
- Length
- 444 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fluorescent protein FP480
- UniProt
- D0VX33
- Ligands
- TUK
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 56% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Fluorescent protein FP480 | protein | 222 | 7% helix, 56% strand | D0VX33 |
Ligands and binding sites
- TUK · 2-[2-[(1~{S})-1-azanyl-3-methylsulfanyl-propyl]-4-(1~{H}-indol-3-ylmethyl)-5-oxidanylidene-2~{H}-imidazol-1-yl]ethanal · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 96 | 0.76 | 0.97 | 27 | TUK |
| 2 | 101 | 0.75 | 0.96 | 26 | TUK |
| 3 | 61 | 0.28 | 0.73 | 14 | empty |
Interfaces
1 interface between chains.
- A–B · 1415 Ų buried · 23 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 covalent (covalent ligand).
Compared structures
- 7BHG · Gene-engineered variant of FusionRed with Trp based chromophore - 2.1A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D0VX33
- Elsewhere: RCSB PDB 7BHG · PDBe 7BHG · UniProt D0VX33
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