MolNFT v1 · #173960 · protein
Crystal structure of the heterocyclic toxin methyltransferase from mycobacterium tuberculosis
7BGG · Heterocyclic toxin methyltransferase (RV0560C): “Crystal structure of the heterocyclic toxin methyltransferase from mycobacterium tuberculosis”. X-ray diffraction, 2 ligands (SAH, NA), 1 pocket (best druggability 0.76). MolNFT v1…
- PDB
- 7BGG
- Type
- protein
- Length
- 216 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Heterocyclic toxin methyltransferase (RV0560C)
- EC
- 2.1.1.374
- UniProt
- P9WKL5
- Ligands
- SAH, NA
- Pockets
- 1 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heterocyclic toxin methyltransferase (RV0560C) (EC 2.1.1.374) | protein | 216 | 31% helix, 28% strand | P9WKL5 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 501 | 0.76 | 0.84 | 60 | SAH, NA |
Compared structures
- 7BGG · Crystal structure of the heterocyclic toxin methyltransferase from Mycobacterium… · the same entry in another collection · chain A against A, TM-score 1.00
- P9WKL5 · AlphaFold monomer V2.0 prediction for 2-heptyl-1-hydroxyquinolin-4(1H)-one… · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P9WKL5
- Elsewhere: RCSB PDB 7BGG · PDBe 7BGG · UniProt P9WKL5
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