MolNFT v1 · #173824 · protein
Native virion of kashmir bee virus at acidic pH
7BC3 · Structural polyprotein: “Native virion of kashmir bee virus at acidic pH”. Electron microscopy, 7 pockets (best druggability 0.73). MolNFT v1 #173824 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7BC3
- Type
- protein
- Length
- 803 residues
- Chains
- 4
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Structural polyprotein
- UniProt
- Q80AG2, Q6SQI6
- Pockets
- 7 · best druggability 0.73
Structure
electron microscopy · 4 distinct chains · 11% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | Structural polyprotein | protein | 58 | 12% helix, 2% strand | Q80AG2 |
| A | Structural polyprotein | protein | 208 | 18% helix, 35% strand | Q6SQI6 |
| C | Structural polyprotein | protein | 289 | 6% helix, 34% strand | Q80AG2 |
| B | Structural polyprotein | protein | 248 | 11% helix, 35% strand | Q80AG2 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 809 | 0.73 | 0.78 | 74 | empty |
| 2 | 106 | 0.66 | 0.90 | 26 | empty |
| 3 | 225 | 0.66 | 0.84 | 40 | empty |
| 4 | 304 | 0.55 | 0.75 | 40 | empty |
| 5 | 118 | 0.35 | 0.73 | 26 | empty |
Interfaces
5 interfaces between chains.
- A–C · 4523 Ų buried · 66 hydrogen bonds · protein-protein
- C–B · 1557 Ų buried · 22 hydrogen bonds · protein-protein
- A–B · 1198 Ų buried · 16 hydrogen bonds · protein-protein
- D–C · 966 Ų buried · 9 hydrogen bonds · protein-protein
- D–A · 233 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 7BC3 · Native virion of Kashmir bee virus at acidic pH · the same entry in another collection · chain C against C, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q80AG2
- Every structure of UniProt Q6SQI6
- Elsewhere: RCSB PDB 7BC3 · PDBe 7BC3 · UniProt Q80AG2 · UniProt Q6SQI6
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