MolNFT v1 · #173721 · protein
Circular permutant of ribosomal protein S6, P54-55 truncated, I8A mutant
7B90 · 30S ribosomal protein S6,30S ribosomal protein S6: “Circular permutant of ribosomal protein S6, P54-55 truncated, I8A mutant”. X-ray diffraction, 15 pockets (best druggability 0.50). MolNFT v1 #173721 on GenesisL1: 3D structure…
- PDB
- 7B90
- Type
- protein
- Length
- 1,032 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 30S ribosomal protein S6,30S ribosomal protein S6
- UniProt
- Q5SLP8
- Pockets
- 15 · best druggability 0.50
Structure
x-ray diffraction · 1 distinct chain · 34% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, J, K, L, C, D, E, F, G, H, I | 30S ribosomal protein S6,30S ribosomal protein S6 | protein | 86 | 34% helix, 37% strand | Q5SLP8 |
Pockets
15 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 228 | 0.50 | 0.76 | 29 | empty |
| 2 | 174 | 0.44 | 0.74 | 27 | empty |
| 3 | 110 | 0.41 | 0.76 | 17 | empty |
| 4 | 131 | 0.40 | 0.74 | 23 | empty |
| 5 | 78 | 0.39 | 0.78 | 17 | empty |
Interfaces
11 interfaces between chains.
- H–I · 832 Ų buried · 20 hydrogen bonds · protein-protein
- D–I · 779 Ų buried · 14 hydrogen bonds · protein-protein
- E–F · 773 Ų buried · 17 hydrogen bonds · protein-protein
- C–G · 760 Ų buried · 17 hydrogen bonds · protein-protein
- D–E · 756 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 7B90 · Circular permutant of ribosomal protein S6, P54-55 truncated, I8A mutant · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SLP8
- Elsewhere: RCSB PDB 7B90 · PDBe 7B90 · UniProt Q5SLP8
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