MolNFT v1 · #173710 · protein

Acinetobacter baumannii multidrug transporter adeb in ooo state

7B8P · Efflux pump membrane transporter: “Acinetobacter baumannii multidrug transporter adeb in ooo state”. Electron microscopy, 20 pockets (best druggability 0.85). MolNFT v1 #173710 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 7B8P
Type: protein
Length: 3,045 residues
Chains: 3
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Efflux pump membrane transporter
UniProt: B0V4F5
Pockets: 20 · best druggability 0.85

Structure

electron microscopy · 1 distinct chain · 52% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Efflux pump membrane transporter	protein	1015	52% helix, 18% strand	B0V4F5

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	671	0.85	0.89	87	empty
2	601	0.84	0.89	81	empty
3	333	0.82	0.92	30	empty
4	366	0.81	0.91	43	empty
5	402	0.76	0.85	56	empty

Interfaces

3 interfaces between chains.

A–B · 3149 Å² buried · 33 hydrogen bonds · protein-protein
B–C · 3144 Å² buried · 33 hydrogen bonds · protein-protein
A–C · 3132 Å² buried · 31 hydrogen bonds · protein-protein

Compared structures

7B8P · Acinetobacter baumannii multidrug transporter AdeB in OOO state · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B0V4F5
Elsewhere: RCSB PDB 7B8P · PDBe 7B8P · UniProt B0V4F5

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.