MolNFT v1 · #173674 · protein

Pilb minor pilin from streptococcus sanguinis

7B7P · Type IV pilus biogenesis protein pilb: “Pilb minor pilin from streptococcus sanguinis”. X-ray diffraction, 2 ligands (MG, CL), 3 pockets (best druggability 0.72). MolNFT v1 #173674 on GenesisL1: 3D structure, binding sites and…

PDB: 7B7P
Type: protein
Length: 840 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Type IV pilus biogenesis protein pilb
UniProt: A0A0B7GP99
Ligands: MG, CL
Pockets: 3 · best druggability 0.72

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Type IV pilus biogenesis protein pilb	protein	420	30% helix, 29% strand	A0A0B7GP99

Ligands and binding sites

MG · Magnesium ion · metal · 2 copies · chains A, B
CL · Chloride ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	571	0.72	0.81	55	MG
2	50	0.28	0.75	12	empty
3	50	0.26	0.74	13	empty

Interfaces

1 interface between chains.

A–B · 715 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

7B7P · PilB minor pilin from Streptococcus sanguinis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A0B7GP99
Elsewhere: RCSB PDB 7B7P · PDBe 7B7P · UniProt A0A0B7GP99

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