MolNFT v1 · #173641 · protein

GSK3-beta in complex with compound (S)-5C

7B6F: “GSK3-beta in complex with compound (S)-5C”. X-ray diffraction, 2 ligands (SZW, SO4). MolNFT v1 #173641 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7B6F
Type: protein
Length: 347 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P49841
Ligands: SZW, SO4

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	347	—	P49841

Ligands and binding sites

SZW · 3-[(3~{S})-3-[(7-chloranyl-9~{H}-pyrimido[4,5-b]indol-4-yl)-methyl-amino]piperidin-1-yl]propanenitrile · ligand · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7B6F · GSK3-beta in complex with compound (S)-5c · the same entry in another collection · chain A against A, TM-score 1.00
P49841 · AlphaFold monomer V2.0 prediction for glycogen synthase kinase-3 beta (P49841) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49841
Elsewhere: RCSB PDB 7B6F · PDBe 7B6F · UniProt P49841

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