MolNFT v1 · #173439 · protein
Crystal structure of the MIZ1-btb-domain
7AZW · Zinc finger and btb domain-containing protein 17 isoform X1: “Crystal structure of the MIZ1-btb-domain”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #173439 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7AZW
- Type
- protein
- Length
- 233 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zinc finger and btb domain-containing protein 17 isoform X1
- Pockets
- 1 · best druggability 0.37
Structure
x-ray diffraction · 2 distinct chains · 55% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc finger and btb domain-containing protein 17 isoform X1 | protein | 119 | 51% helix, 12% strand | — |
| B | Zinc finger and btb domain-containing protein 17 isoform X1 | protein | 114 | 60% helix, 12% strand | — |
Ligands and binding sites
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.37 | 0.75 | 15 | GOL |
Interfaces
1 interface between chains.
- A–B · 1645 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 7AZW · Crystal structure of the MIZ1-BTB-domain · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7AZW · PDBe 7AZW
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