MolNFT v1 · #173323 · protein
Mertk kinase domain with type 1 inhibitor from a DNA-encoded library
7AW3: “Mertk kinase domain with type 1 inhibitor from a DNA-encoded library”. X-ray diffraction, 1 ligand (S4Z). MolNFT v1 #173323 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AW3
- Type
- protein
- Length
- 269 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q12866
- Ligands
- S4Z
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 269 | — | Q12866 |
Ligands and binding sites
- S4Z · 2-(1-((5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carboxamido)methyl)-2-azabicyclo[2.1.1]hexan-2-yl)-N-methyl-4-(trifluoromethyl)thiazole-5-carboxamide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7AW3 · MerTK kinase domain with type 1 inhibitor from a DNA-encoded library · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12866
- Elsewhere: RCSB PDB 7AW3 · PDBe 7AW3 · UniProt Q12866
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