MolNFT v1 · #173227 · protein
Crystal structure of inactive ESTD11 S144A
7AT2: “Crystal structure of inactive ESTD11 S144A”. X-ray diffraction, 4 pockets (best druggability 0.79). MolNFT v1 #173227 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AT2
- Type
- protein
- Length
- 590 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- ESTD11 S144A
- Pockets
- 4 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | ESTD11 S144A | protein | 295 | 44% helix, 17% strand | — |
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 250 | 0.79 | 0.91 | 42 | empty |
| 2 | 396 | 0.78 | 0.87 | 61 | empty |
| 3 | 183 | 0.46 | 0.75 | 26 | empty |
| 4 | 54 | 0.29 | 0.75 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 471 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 7AT2 · Crystal structure of inactive EstD11 S144A · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 7AT2 · PDBe 7AT2
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