MolNFT v1 · #172941 · protein

Structure of DYRK1A in complex with compound 3

7AJ2: “Structure of DYRK1A in complex with compound 3”. X-ray diffraction, 2 ligands (RJ5, CL). MolNFT v1 #172941 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7AJ2
Type: protein
Length: 330 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q13627
Ligands: RJ5, CL

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	330	—	Q13627

Ligands and binding sites

RJ5 · 4-(4-methoxyphenyl)pyridin-2-amine · ligand · chains A
CL · Chloride ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7AJ2 · Structure of DYRK1A in complex with compound 3 · the same entry in another collection · chain A against A, TM-score 1.00
Q13627 · AlphaFold monomer V2.0 prediction for dual specificity tyrosine… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13627
Elsewhere: RCSB PDB 7AJ2 · PDBe 7AJ2 · UniProt Q13627

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