MolNFT v1 · #172905 · protein

Structure of the N-domain of the K+/H+ antiporter subunit khtt at pH 7.5

7AHT · K(+)/H(+) antiporter subunit khtt: “Structure of the N-domain of the K+/H+ antiporter subunit khtt at pH 7.5”. X-ray diffraction, 1 pocket (best druggability 0.79). MolNFT v1 #172905 on GenesisL1: 3D structure, binding sites and…

PDB: 7AHT
Type: protein
Length: 123 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: K(+)/H(+) antiporter subunit khtt
UniProt: O07535
Pockets: 1 · best druggability 0.79

Structure

x-ray diffraction · 2 distinct chains · 19% helix, 50% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	K(+)/H(+) antiporter subunit khtt	protein	65	17% helix, 49% strand	O07535
B	K(+)/H(+) antiporter subunit khtt	protein	58	21% helix, 50% strand	O07535

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.79	0.95	26	empty

Interfaces

1 interface between chains.

A–B · 1296 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

7AHT · Structure of the N-domain of the K+/H+ antiporter subunit KhtT at pH 7.5 · the same entry in another collection · chain A against A, TM-score 1.00
O07535 · AlphaFold monomer V2.0 prediction for K(+)/H(+) antiporter subunit khtt (O07535) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O07535
Elsewhere: RCSB PDB 7AHT · PDBe 7AHT · UniProt O07535

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.