MolNFT v1 · #172804 · protein
Crystal structure of HEPN(H107A-Y109F) toxin in complex with mnt antitoxin
7AE2 · Hepn toxin: “Crystal structure of HEPN(H107A-Y109F) toxin in complex with mnt antitoxin”. X-ray diffraction, 1 pocket (best druggability 0.60). MolNFT v1 #172804 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AE2
- Type
- protein
- Length
- 282 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hepn toxin; Mnt antitoxin
- UniProt
- A0A0B0QJR1, A0A0B0QJN8
- Pockets
- 1 · best druggability 0.60
Structure
x-ray diffraction · 2 distinct chains · 67% helix, 9% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Hepn toxin | protein | 141 | 78% helix, 0% strand | A0A0B0QJR1 |
| B | Mnt antitoxin | protein | 141 | 57% helix, 17% strand | A0A0B0QJN8 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 440 | 0.60 | 0.75 | 33 | empty |
Interfaces
1 interface between chains.
- A–B · 880 Ų buried · 11 hydrogen bonds · protein-protein
Compared structures
- 7AE2 · Crystal structure of HEPN(H107A-Y109F) toxin in complex with MNT antitoxin · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0B0QJR1
- Every structure of UniProt A0A0B0QJN8
- Elsewhere: RCSB PDB 7AE2 · PDBe 7AE2 · UniProt A0A0B0QJR1 · UniProt A0A0B0QJN8
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