MolNFT v1 · #172796 · protein
Orf virus apoptosis inhibitor ORFV125
7ADS: “Orf virus apoptosis inhibitor ORFV125”. X-ray diffraction, 3 ligands (NA, MG, CL), 2 pockets (best druggability 0.57). MolNFT v1 #172796 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7ADS
- Type
- protein
- Length
- 135 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Apoptosis inhibitor
- UniProt
- A0A0R8HV90
- Ligands
- NA, MG, CL
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Apoptosis inhibitor | protein | 135 | 77% helix, 0% strand | A0A0R8HV90 |
Ligands and binding sites
- NA · Sodium ion · metal · 5 copies · chains A
- MG · Magnesium ion · metal · 4 copies · chains A
- CL · Chloride ion · ion · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 397 | 0.57 | 0.74 | 39 | empty |
| 2 | 80 | 0.34 | 0.75 | 17 | empty |
Compared structures
- 7ADS · Orf virus Apoptosis inhibitor ORFV125 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0R8HV90
- Elsewhere: RCSB PDB 7ADS · PDBe 7ADS · UniProt A0A0R8HV90
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