MolNFT v1 · #172709 · protein
Crystal structure of mertk kinase domain in complex with UNC2025
7AB2: “Crystal structure of mertk kinase domain in complex with UNC2025”. X-ray diffraction, 2 ligands (R6N, CL). MolNFT v1 #172709 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7AB2
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q12866
- Ligands
- R6N, CL
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 270 | — | Q12866 |
Ligands and binding sites
- R6N · 4-[2-(butylamino)-5-[4-[(4-methylpiperazin-1-yl) methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol · ligand · chains A
- CL · Chloride ion · ion · 4 copies · chains A
- DMS · Dimethyl sulfoxide · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7AB2 · Crystal structure of MerTK kinase domain in complex with UNC2025 · the same entry in another collection · chain A against A, TM-score 1.00
- Q12866 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase mer (Q12866) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12866
- Elsewhere: RCSB PDB 7AB2 · PDBe 7AB2 · UniProt Q12866
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