MolNFT v1 · #17257 · protein

Crystal structure of thermus thermophilus HB8 H-protein of the glycine cleavage system

1ONL · Glycine cleavage system H protein: “Crystal structure of thermus thermophilus HB8 H-protein of the glycine cleavage system”. X-ray diffraction, 5 pockets (best druggability 0.69). MolNFT v1 #17257 on GenesisL1: 3D structure, binding…

PDB: 1ONL
Type: protein
Length: 381 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glycine cleavage system H protein
UniProt: P83697
Pockets: 5 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Glycine cleavage system H protein	protein	127	24% helix, 37% strand	P83697

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	648	0.69	0.77	69	empty
2	147	0.61	0.84	26	empty
3	158	0.49	0.78	31	empty
4	73	0.29	0.73	17	empty
5	53	0.26	0.74	15	empty

Interfaces

3 interfaces between chains.

A–B · 635 Å² buried · 9 hydrogen bonds · protein-protein
B–C · 387 Å² buried · 4 hydrogen bonds · protein-protein
A–C · 376 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

1ONL · Crystal structure of Thermus thermophilus HB8 H-protein of the glycine cleavage system · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P83697
Elsewhere: RCSB PDB 1ONL · PDBe 1ONL · UniProt P83697

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