MolNFT v1 · #172520 · protein

Structure of DYRK1A in complex with compound 4

7A4Z: “Structure of DYRK1A in complex with compound 4”. X-ray diffraction, 1 ligand (6SD). MolNFT v1 #172520 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7A4Z
Type: protein
Length: 331 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q13627
Ligands: 6SD

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	331	—	Q13627

Ligands and binding sites

6SD · 3-(4-methoxyphenyl)-1~{H}-pyrazol-5-amine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7A4Z · Structure of DYRK1A in complex with compound 4 · the same entry in another collection · chain A against A, TM-score 1.00
Q13627 · AlphaFold monomer V2.0 prediction for dual specificity tyrosine… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q13627
Elsewhere: RCSB PDB 7A4Z · PDBe 7A4Z · UniProt Q13627

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.