MolNFT v1 · #172329 · protein
Crystal structure of mlkl executioner domain in complex with a covalent inhibitor
6ZZ1: “Crystal structure of mlkl executioner domain in complex with a covalent inhibitor”. X-ray diffraction, 1 ligand (QOK). MolNFT v1 #172329 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ZZ1
- Type
- protein
- Length
- 284 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8NB16
- Ligands
- QOK
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 144 | — | Q8NB16 |
| B | — | protein | 140 | — | Q8NB16 |
Ligands and binding sites
- QOK · 7-(2-methoxyethoxymethyl)-1,3-dimethyl-purine-2,6-dione · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6ZZ1 · Crystal structure of MLKL executioner domain in complex with a covalent inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
- Q8NB16 · AlphaFold monomer V2.0 prediction for mixed lineage kinase domain- like protein (Q8NB16) · a predicted model of the same protein · chain B against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NB16
- Elsewhere: RCSB PDB 6ZZ1 · PDBe 6ZZ1 · UniProt Q8NB16
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