MolNFT v1 · #172241 · protein
Crystal structure of human acetylcholinesterase in complex with ((6- ((2E,4E)-5-(BENZO[D][1,3]DIOXOL-5-YL)PENTA-2,4-DIENAMIDO)HEXYL) triphenylphosphonium bromide)
6ZWE: “Crystal structure of human acetylcholinesterase in complex with ((6…”. X-ray diffraction, 6 ligands (QRH, NAG, FUC). MolNFT v1 #172241 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ZWE
- Type
- protein
- Length
- 1,073 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P22303
- Ligands
- QRH, NAG, FUC, CL, SO4, BR
Structure
x-ray diffraction · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 533 | — | P22303 |
| B | — | protein | 540 | — | P22303 |
Ligands and binding sites
- QRH · (2~{E},4~{E})-5-(1,3-benzodioxol-5-yl)-~{N}-[6-(triphenyl-$l^{5}-phosphanyl)hexyl]penta-2,4-dienamide · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 7 copies · chains A, B
- FUC · alpha-L-fucopyranose · sugar · 2 copies · chains A
- CL · Chloride ion · ion · 23 copies · chains A, B
- SO4 · Sulfate ion · ion · 18 copies · chains A, B
- BR · Bromide ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22303
- Elsewhere: RCSB PDB 6ZWE · PDBe 6ZWE · UniProt P22303
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