GL1X · GenesisL1 explorer

MolNFT v1 · #172166 · protein

Assembly intermediates of orthoreovirus captured in the cell

6ZTS · Lambda-1: “Assembly intermediates of orthoreovirus captured in the cell”. Electron microscopy, 20 pockets (best druggability 0.90). MolNFT v1 #172166 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6ZTS
Type
protein
Length
1,941 residues
Chains
2
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Lambda-1
UniProt
A0A023VYS9
Pockets
20 · best druggability 0.90

Structure

electron microscopy · 2 distinct chains · 34% helix, 12% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ALambda-1protein97433% helix, 13% strandA0A023VYS9
BLambda-1protein96735% helix, 11% strandA0A023VYS9

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111150.900.92159empty
27540.900.94124empty
311380.900.91162empty
410440.880.89129empty
53320.860.9552empty

Interfaces

1 interface between chains.

  • A–B · 947 Ų buried · 8 hydrogen bonds · protein-protein

Compared structures

  • 6ZTS · Assembly intermediates of orthoreovirus captured in the cell · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.