GL1X · GenesisL1 explorer

MolNFT v1 · #17206 · protein

Solution NMR structure of the mitochondrial protein import receptor TOM20 from rat in a complex with a presequence peptide derived from rat aldehyde dehydrogenase (aldh)

1OM2 · Protein (mitochondrial import receptor subunit TOM20): “Solution NMR structure of the mitochondrial protein import receptor TOM20 from rat in a complex with a…”. Solution nmr, 1 pocket (best druggability 0.56). MolNFT v1 #17206 on…

PDB
1OM2
Type
protein
Length
106 residues
Chains
2
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein (mitochondrial import receptor subunit TOM20); Protein (mitochondrial aldehyde…
EC
1.2.1.3
UniProt
Q62760, P11884
Pockets
1 · best druggability 0.56

Structure

solution nmr · 2 distinct chains · 65% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein (mitochondrial import receptor subunit TOM20)protein9568% helix, 0% strandQ62760
BProtein (mitochondrial aldehyde dehydrogenase) (EC 1.2.1.3)protein1136% helix, 0% strandP11884

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1770.560.8617empty

Interfaces

1 interface between chains.

  • A–B · 537 Ų buried · 5 hydrogen bonds · protein-protein

Compared structures

  • 1OM2 · Solution NMR structure of the mitochondrial protein import receptor TOM20 from rat in a… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q62760 · AlphaFold monomer V2.0 prediction for mitochondrial import receptor subunit TOM20 homolog… · a predicted model of the same protein · chain A against A, TM-score 0.64
  • P11884 · AlphaFold monomer V2.0 prediction for aldehyde dehydrogenase, mitochondrial (P11884) · a predicted model of the same protein · chain B against A, TM-score 0.35

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.