MolNFT v1 · #172050 · protein

Nonstructural protein 10 (NSP10) from SARS cov-2

6ZPE · Replicase polyprotein 1AB: “Nonstructural protein 10 (NSP10) from SARS cov-2”. X-ray diffraction, 2 ligands (ZN, CL), 1 pocket (best druggability 0.46). MolNFT v1 #172050 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ZPE
Type: protein
Length: 124 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Replicase polyprotein 1AB
EC: 3.4.19.12, 3.4.22.-, 3.4.22.69, 2.7.7.48, 3.6.4.12, 3.6.4.13, 3.1.13.-, 3.1.-.-, 2.1.1.-
UniProt: P0DTD1
Ligands: ZN, CL
Pockets: 1 · best druggability 0.46

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 12% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Replicase polyprotein 1AB (EC 3.4.19.12, 3.4.22.-, 3.4.22.69, 2.7.7.48, 3.6.4.12, 3.6.4.13, 3.1.13.-, 3.1.-.-, 2.1.1.-)	protein	124	30% helix, 12% strand	P0DTD1

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A
CL · Chloride ion · ion · 3 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	116	0.46	0.78	17	GOL

Compared structures

6ZPE · Nonstructural protein 10 (nsp10) from SARS CoV-2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0DTD1
Elsewhere: RCSB PDB 6ZPE · PDBe 6ZPE · UniProt P0DTD1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.