MolNFT v1 · #171935 · protein
Solution structure of unliganded mlkl executioner domain
6ZLE · Mixed lineage kinase domain-like protein: “Solution structure of unliganded mlkl executioner domain”. Solution nmr, 2 pockets (best druggability 0.66). MolNFT v1 #171935 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ZLE
- Type
- protein
- Length
- 157 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Mixed lineage kinase domain-like protein
- UniProt
- Q8NB16
- Pockets
- 2 · best druggability 0.66
Structure
solution nmr · 1 distinct chain · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Mixed lineage kinase domain-like protein | protein | 157 | 75% helix, 0% strand | Q8NB16 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 138 | 0.66 | 0.87 | 28 | empty |
| 2 | 102 | 0.57 | 0.85 | 20 | empty |
Compared structures
- 6ZLE · Solution structure of unliganded MLKL executioner domain · the same entry in another collection · chain A against A, TM-score 1.00
- Q8NB16 · AlphaFold monomer V2.0 prediction for mixed lineage kinase domain- like protein (Q8NB16) · a predicted model of the same protein · chain A against A, TM-score 0.83
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8NB16
- Elsewhere: RCSB PDB 6ZLE · PDBe 6ZLE · UniProt Q8NB16
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