Fucose-binding lectin from burkholderia ambifaria (bambl) in complex with a fucosyl derivative

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 69% strand (DSSP).

Ligands and binding sites

• QJB · 2-[(2~{S},3~{S},4~{R},4~{A}~{S},10~{A}~{S})-2-methyl-3, 4-bis(oxidanyl)-3,4,4~{A},10~{A}-tetrahydro-2~{H}-pyrano[2,3-b][1,4]benzoxathiin-7-yl]-~{N}-(3-oxidanylpropyl)ethanamide · ligand · 12 copies · chains A, B, C, D, E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Interfaces

7 interfaces between chains.

• E–F · 732 Ų buried · 9 hydrogen bonds · protein-protein
• A–B · 722 Ų buried · 10 hydrogen bonds · protein-protein
• A–C · 711 Ų buried · 10 hydrogen bonds · protein-protein
• D–E · 708 Ų buried · 9 hydrogen bonds · protein-protein
• B–C · 699 Ų buried · 10 hydrogen bonds · protein-protein

Compared structures

• 6ZFC · Fucose-binding lectin from Burkholderia ambifaria (BamBL) in complex with a fucosyl… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q0B4G1
• Elsewhere: RCSB PDB 6ZFC · PDBe 6ZFC · UniProt Q0B4G1