MolNFT v1 · #171664 · protein

Crystal structure of BRD4-BD1 in complex with nvs-bet-1

6ZCI: “Crystal structure of BRD4-BD1 in complex with nvs-bet-1”. X-ray diffraction, 1 ligand (QFN). MolNFT v1 #171664 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6ZCI
Type: protein
Length: 126 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: O60885
Ligands: QFN

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	126	—	O60885

Ligands and binding sites

QFN · (4~{R})-4-(4-chlorophenyl)-1-cyclopropyl-5-(1,5-dimethyl-6-oxidanylidene-pyridin-3-yl)-3-methyl-4~{H}-pyrrolo[3,4-c]pyrazol-6-one · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6ZCI · Crystal structure of BRD4-BD1 in complex with NVS-BET-1 · the same entry in another collection · chain A against A, TM-score 1.00
O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O60885
Elsewhere: RCSB PDB 6ZCI · PDBe 6ZCI · UniProt O60885

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