MolNFT v1 · #171557 · protein
Fructo-oligosaccharide transporter bt 1762-63
6Z9A · Susd homolog: “Fructo-oligosaccharide transporter bt 1762-63”. X-ray diffraction, 3 ligands (FRU, MG, CL), 20 pockets (best druggability 0.82). MolNFT v1 #171557 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Z9A
- Type
- protein
- Length
- 1,473 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Susd homolog; Susc homolog
- UniProt
- Q8A6W4, Q8A6W3
- Ligands
- FRU, MG, CL
- Pockets
- 20 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 22% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Susd homolog | protein | 552 | 43% helix, 8% strand | Q8A6W4 |
| B | Susc homolog | protein | 921 | 9% helix, 45% strand | Q8A6W3 |
Ligands and binding sites
- FRU · beta-D-fructofuranose · sugar · 7 copies · chains B, A
- MG · Magnesium ion · metal · chains B
- CL · Chloride ion · ion · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 12 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 167 | 0.82 | 0.97 | 40 | empty |
| 2 | 678 | 0.77 | 0.83 | 82 | empty |
| 3 | 492 | 0.70 | 0.80 | 49 | empty |
| 4 | 51 | 0.68 | 0.98 | 28 | empty |
| 5 | 379 | 0.67 | 0.81 | 49 | empty |
Interfaces
1 interface between chains.
- A–B · 4026 Ų buried · 70 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 6Z9A · Fructo-oligosaccharide transporter BT 1762-63 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A6W4
- Every structure of UniProt Q8A6W3
- Elsewhere: RCSB PDB 6Z9A · PDBe 6Z9A · UniProt Q8A6W4 · UniProt Q8A6W3
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