MolNFT v1 · #171488 · protein
Poliovirus type 3 (strain saukett) stabilised virus-like particle (PV3 SC8) from a mammalian expression system.
6Z6W · Capsid proteins, VP1: “Poliovirus type 3 (strain saukett) stabilised virus-like particle (PV3 SC8) from a mammalian expression…”. Electron microscopy, 1 ligand (SPH), 7 pockets (best druggability 0.76). MolNFT v1 #171488 on…
- PDB
- 6Z6W
- Type
- protein
- Length
- 713 residues
- Chains
- 3
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Capsid proteins, VP1; Capsid proteins, VP2; Capsid proteins, VP3
- UniProt
- Q84895, Q84896
- Ligands
- SPH
- Pockets
- 7 · best druggability 0.76
Structure
electron microscopy · 3 distinct chains · 9% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| 1 | Capsid proteins, VP1 | protein | 232 | 8% helix, 34% strand | Q84895 |
| 0 | Capsid proteins, VP2 | protein | 246 | 10% helix, 39% strand | Q84896 |
| 3 | Capsid proteins, VP3 | protein | 235 | 8% helix, 33% strand | Q84895 |
Ligands and binding sites
- SPH · Sphingosine · ligand · chains 1, 3
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 406 | 0.76 | 0.85 | 54 | SPH |
| 2 | 62 | 0.41 | 0.81 | 21 | empty |
| 3 | 50 | 0.40 | 0.82 | 17 | empty |
| 4 | 80 | 0.36 | 0.76 | 18 | empty |
| 5 | 77 | 0.34 | 0.76 | 25 | empty |
Interfaces
3 interfaces between chains.
- 1–3 · 3218 Ų buried · 59 hydrogen bonds · protein-protein
- 1–0 · 2080 Ų buried · 26 hydrogen bonds · protein-protein
- 0–3 · 1618 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 6Z6W · Poliovirus type 3 (strain Saukett) stabilised virus-like particle (PV3 SC8) from a… · the same entry in another collection · chain 1 against 1, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q84895
- Every structure of UniProt Q84896
- Elsewhere: RCSB PDB 6Z6W · PDBe 6Z6W · UniProt Q84895 · UniProt Q84896
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.