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MolNFT v1 · #171362 · protein

Structure of EIF4G1 (37-49) - PUB1 RRM3 chimera in solution

6Z29 · Eukaryotic initiation factor 4F subunit P150,NUCLEAR and…: “Structure of EIF4G1 (37-49) - PUB1 RRM3 chimera in solution”. Solution nmr, 1 pocket (best druggability 0.42). MolNFT v1 #171362 on GenesisL1: 3D structure, binding sites…

PDB
6Z29
Type
protein
Length
116 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Eukaryotic initiation factor 4F subunit P150,NUCLEAR and cytoplasmic polyadenylated…
UniProt
P39935, P32588
Pockets
1 · best druggability 0.42

Structure

solution nmr · 1 distinct chain · 24% helix, 5% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AEukaryotic initiation factor 4F subunit P150,NUCLEAR and cytoplasmic polyadenylated RNA-binding protein PUB1protein11624% helix, 5% strandP39935, P32588

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11550.420.7425empty

Compared structures

  • 6Z29 · Structure of eIF4G1 (37-49) - PUB1 RRM3 chimera in solution · the same entry in another collection · chain A against A, TM-score 1.00
  • P32588 · AlphaFold monomer V2.0 prediction for nuclear and cytoplasmic polyadenylated RNA-binding… · a predicted model of the same protein · chain A against A, TM-score 0.75
  • P39935 · AlphaFold monomer V2.0 prediction for eukaryotic initiation factor 4F subunit P150… · a predicted model of the same protein · chain A against A, TM-score 0.36

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