MolNFT v1 · #171326 · protein
Human wtsting in complex with 3',3'-C-di-AMP
6Z15 · Stimulator of interferon protein: “Human wtsting in complex with 3',3'-C-di-AMP”. X-ray diffraction, 1 ligand (2BA), 1 pocket (best druggability 0.41). MolNFT v1 #171326 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6Z15
- Type
- protein
- Length
- 179 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Stimulator of interferon protein
- UniProt
- A0A2R3XZB7
- Ligands
- 2BA
- Pockets
- 1 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 47% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Stimulator of interferon protein | protein | 179 | 47% helix, 26% strand | A0A2R3XZB7 |
Ligands and binding sites
- 2BA · (2r,3r,3as,5r,7ar,9r,10r,10as,12r,14ar)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-D:3', 2'-J][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5, 10,12-tetrol 5,12-dioxide · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 144 | 0.41 | 0.74 | 24 | 2BA |
Compared structures
- 6Z15 · Human wtSTING in complex with 3',3'-c-di-AMP · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A2R3XZB7
- Elsewhere: RCSB PDB 6Z15 · PDBe 6Z15 · UniProt A0A2R3XZB7
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