MolNFT v1 · #17125 · protein + DNA
Novel and retro binding modes in cytotoxic ribonucleases from rana catesbeiana of two crystal structures complexed with D(APCPGPA) and (2',5'CPG)
1OJ8 · Rc-RNASE6 ribonuclease: “Novel and retro binding modes in cytotoxic ribonucleases from rana catesbeiana of two crystal structures…”. X-ray diffraction, 1 ligand (SO4). MolNFT v1 #17125 on GenesisL1: 3D structure, binding sites and…
- PDB
- 1OJ8
- Type
- protein + DNA
- Length
- 109 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Rc-RNASE6 ribonuclease; 5'-D(*AP*CP*GP*AP)-3'
- UniProt
- Q9DFY5
- Ligands
- SO4
Structure
x-ray diffraction · 2 distinct chains · 17% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Rc-RNASE6 ribonuclease | protein | 105 | 17% helix, 38% strand | Q9DFY5 |
| B | 5'-D(*AP*CP*GP*AP)-3' | dna | 4 | — | — |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 247 Ų buried · 7 hydrogen bonds · protein-nucleic
Modifications
Observed in the structure: 4 disulfide, 1 modified (disulfide, cyclization).
Compared structures
- 1OJ8 · Novel and retro Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9DFY5
- Elsewhere: RCSB PDB 1OJ8 · PDBe 1OJ8 · UniProt Q9DFY5
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