MolNFT v1 · #171230 · protein
Higher resolution structure of the N-terminal module of the human SWI/SNF-subunit BAF155/SMARCC1
6YXP · SWI/SNF complex subunit SMARCC1: “Higher resolution structure of the N-terminal module of the human SWI/SNF-subunit BAF155/SMARCC1”. X-ray diffraction, 7 pockets (best druggability 0.76). MolNFT v1 #171230 on GenesisL1: 3D…
- PDB
- 6YXP
- Type
- protein
- Length
- 543 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SWI/SNF complex subunit SMARCC1
- UniProt
- Q92922
- Pockets
- 7 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SWI/SNF complex subunit SMARCC1 | protein | 271 | 44% helix, 14% strand | Q92922 |
| B | SWI/SNF complex subunit SMARCC1 | protein | 272 | 44% helix, 14% strand | Q92922 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 966 | 0.76 | 0.79 | 81 | empty |
| 2 | 569 | 0.74 | 0.81 | 54 | empty |
| 3 | 489 | 0.73 | 0.82 | 51 | empty |
| 4 | 73 | 0.38 | 0.78 | 16 | empty |
| 5 | 66 | 0.30 | 0.74 | 10 | empty |
Interfaces
1 interface between chains.
- A–B · 517 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 6YXP · Higher resolution structure of the N-terminal module of the human SWI/SNF-subunit… · the same entry in another collection · chain A against A, TM-score 1.00
- Q92922 · AlphaFold monomer V2.0 prediction for SWI/SNF complex subunit SMARCC1 (Q92922) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92922
- Elsewhere: RCSB PDB 6YXP · PDBe 6YXP · UniProt Q92922
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.