MolNFT v1 · #171149 · protein

Structure of human B(0,+)AT1

6YV1 · B(0,+)-type amino acid transporter 1: “Structure of human B(0,+)AT1”. Electron microscopy, 4 pockets (best druggability 0.65). MolNFT v1 #171149 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6YV1
Type: protein
Length: 328 residues
Chains: 1
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: B(0,+)-type amino acid transporter 1
UniProt: P82251
Pockets: 4 · best druggability 0.65

Structure

electron microscopy · 1 distinct chain · 68% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	B(0,+)-type amino acid transporter 1	protein	328	68% helix, 1% strand	P82251

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	478	0.65	0.77	48	empty
2	101	0.46	0.80	21	empty
3	72	0.45	0.82	17	empty
4	96	0.36	0.74	15	empty

Compared structures

6YV1 · Structure of human b(0,+)AT1 · the same entry in another collection · chain A against A, TM-score 1.00
P82251 · AlphaFold monomer V2.0 prediction for B(0,+)-type amino acid transporter 1 (P82251) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P82251
Elsewhere: RCSB PDB 6YV1 · PDBe 6YV1 · UniProt P82251

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.