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MolNFT v1 · #171088 · protein

Cryo-EM structure of T7 bacteriophage DNA translocation GP15 core protein intermediate assembly

6YSZ · Internal virion protein GP15: “Cryo-EM structure of T7 bacteriophage DNA translocation GP15 core protein intermediate assembly”. Electron microscopy, 20 pockets (best druggability 0.66). MolNFT v1 #171088 on GenesisL1: 3D structure…

PDB
6YSZ
Type
protein
Length
1,896 residues
Chains
6
Method
electron microscopy
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Internal virion protein GP15
UniProt
P03725
Pockets
20 · best druggability 0.66

Structure

electron microscopy · 1 distinct chain · 72% helix, 2% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, C, D, E, FInternal virion protein GP15protein31672% helix, 2% strandP03725

Pockets

20 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11360.660.8821empty
21330.650.8821empty
31360.650.8822empty
41290.650.8822empty
51260.630.8721empty

Interfaces

6 interfaces between chains.

  • C–D · 2576 Ų buried · 38 hydrogen bonds · protein-protein
  • A–B · 2574 Ų buried · 38 hydrogen bonds · protein-protein
  • E–F · 2570 Ų buried · 39 hydrogen bonds · protein-protein
  • B–C · 2568 Ų buried · 39 hydrogen bonds · protein-protein
  • A–F · 2567 Ų buried · 37 hydrogen bonds · protein-protein

Compared structures

  • 6YSZ · Cryo-EM structure of T7 bacteriophage DNA translocation gp15 core protein intermediate… · the same entry in another collection · chain A against A, TM-score 1.00

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