MolNFT v1 · #170965 · protein

Focal adhesion kinase catalytic domain in complex with 6-[4-(3- methanesulfonyl-benzylamino)-5-trifluoromethyl-pyrimidin-2-ylamino]- 3,4-dihydro-1H-quinolin-2-one

6YOJ: “Focal adhesion kinase catalytic domain in complex with 6-[4-(3…”. X-ray diffraction, 1 ligand (P4N). MolNFT v1 #170965 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6YOJ
Type: protein
Length: 259 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: Q05397
Ligands: P4N

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	259	—	Q05397

Ligands and binding sites

P4N · 6-[[4-[(3-methylsulfonylphenyl)methylamino]-5-(trifluoromethyl)pyrimidin-2-yl]amino]-3,4-dihydro-1~{H}-quinolin-2-one · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6YOJ · FOCAL ADHESION KINASE CATALYTIC DOMAIN IN COMPLEX WITH… · the same entry in another collection · chain A against A, TM-score 1.00
Q05397 · AlphaFold monomer V2.0 prediction for focal adhesion kinase 1 (Q05397) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q05397
Elsewhere: RCSB PDB 6YOJ · PDBe 6YOJ · UniProt Q05397

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