MolNFT v1 · #170669 · protein

Morganella morganii TCDA4 in complex with porcine mucosa heparin

6YEW · Insecticidal toxin protein: “Morganella morganii TCDA4 in complex with porcine mucosa heparin”. Electron microscopy, 20 pockets (best druggability 0.87). MolNFT v1 #170669 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 6YEW
Type: protein
Length: 11,425 residues
Chains: 5
Method: electron microscopy
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Insecticidal toxin protein
Pockets: 20 · best druggability 0.87

Structure

electron microscopy · 1 distinct chain · 44% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E	Insecticidal toxin protein	protein	2285	44% helix, 14% strand	—

Pockets

20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1076	0.87	0.88	153	empty
2	275	0.83	0.95	41	empty
3	732	0.83	0.86	82	empty
4	1006	0.82	0.83	77	empty
5	854	0.82	0.84	65	empty

Interfaces

10 interfaces between chains.

D–E · 10465 Å² buried · 99 hydrogen bonds · protein-protein
B–C · 10400 Å² buried · 96 hydrogen bonds · protein-protein
A–E · 10385 Å² buried · 98 hydrogen bonds · protein-protein
C–D · 10382 Å² buried · 93 hydrogen bonds · protein-protein
A–B · 10355 Å² buried · 95 hydrogen bonds · protein-protein

Compared structures

6YEW · Morganella morganii TcdA4 in complex with porcine mucosa heparin · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6YEW · PDBe 6YEW

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