Crystal structure of a native bcse (217-523) - bcsr-bcsq (R156E mutant) complex with C-di-gmp and ATP bound

Structure

x-ray diffraction · 5 distinct chains.

Ligands and binding sites

• C2E · 9,9'-[(2r,3r,3as,5s,7ar,9r,10r,10as,12s,14ar)-3,5,10, 12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3, 2-D:3',2'-J][1,3,7,9,2, 8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one) · ligand · 4 copies · chains E, F
• ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains A, B
• MG · Magnesium ion · metal · 2 copies · chains A, B
• GOL · Glycerol · additive · 2 copies · chains E, F

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

• 6YBB · Crystal structure of a native BcsE (217-523) - BcsR-BcsQ (R156E mutant) complex with… · the same entry in another collection · chain F against F, TM-score 1.00
• P37657 · AlphaFold monomer V2.0 prediction for cyclic di-gmp binding protein bcse (P37657) · a predicted model of the same protein · chain E against A, TM-score 0.92

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt A0A0B1KWQ0
• Every structure of UniProt J7QAC9
• Every structure of UniProt P37657
• Elsewhere: RCSB PDB 6YBB · PDBe 6YBB · UniProt A0A0B1KWQ0 · UniProt J7QAC9 · UniProt P37657