MolNFT v1 · #17035 · protein

Structure of the bifunctional dctp deaminase-dutpase from methanocaldococcus jannaschii

1OGH · Bifunctional DEAMINASE/DIPHOSPHATASE: “Structure of the bifunctional dctp deaminase-dutpase from methanocaldococcus jannaschii”. X-ray diffraction, 1 pocket (best druggability 0.34). MolNFT v1 #17035 on GenesisL1: 3D structure…

PDB: 1OGH
Type: protein
Length: 356 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Bifunctional DEAMINASE/DIPHOSPHATASE
EC: 3.5.4.13, 3.6.1.23
UniProt: Q57872
Pockets: 1 · best druggability 0.34

Structure

x-ray diffraction · 2 distinct chains · 15% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Bifunctional DEAMINASE/DIPHOSPHATASE (EC 3.5.4.13, 3.6.1.23)	protein	175	15% helix, 42% strand	Q57872
B	Bifunctional DEAMINASE/DIPHOSPHATASE (EC 3.5.4.13, 3.6.1.23)	protein	181	15% helix, 40% strand	Q57872

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	106	0.34	0.72	20	empty

Interfaces

1 interface between chains.

A–B · 19 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

1OGH · Structure of the bifunctional dCTP deaminase-dUTPase from Methanocaldococcus jannaschii · the same entry in another collection · chain A against A, TM-score 1.00
Q57872 · AlphaFold monomer V2.0 prediction for dctp deaminase, dump-forming (Q57872) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q57872
Elsewhere: RCSB PDB 1OGH · PDBe 1OGH · UniProt Q57872

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