MolNFT v1 · #170193 · protein

Arabidopsis UV-B photoreceptor UVR8 mutant D96N D107N W285A

6XZM · Ultraviolet-B receptor UVR8: “Arabidopsis UV-B photoreceptor UVR8 mutant D96N D107N W285A”. X-ray diffraction, 1 ligand (NO3), 4 pockets (best druggability 0.76). MolNFT v1 #170193 on GenesisL1: 3D structure, binding sites and…

PDB: 6XZM
Type: protein
Length: 734 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ultraviolet-B receptor UVR8
UniProt: Q9FN03
Ligands: NO3
Pockets: 4 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Ultraviolet-B receptor UVR8	protein	367	6% helix, 44% strand	Q9FN03

Ligands and binding sites

NO3 · Nitrate ion · ion · 4 copies · chains A, B
PEG · Di(hydroxyethyl)ether · additive · 3 copies · chains A, B
PGE · Triethylene glycol · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	426	0.76	0.85	47	NO3
2	465	0.74	0.83	48	empty
3	561	0.71	0.80	59	PEG
4	97	0.43	0.79	19	empty

Interfaces

1 interface between chains.

A–B · 819 Å² buried · 16 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (artifact).

Compared structures

6XZM · Arabidopsis UV-B photoreceptor UVR8 mutant D96N D107N W285A · the same entry in another collection · chain A against A, TM-score 1.00
Q9FN03 · AlphaFold monomer V2.0 prediction for ultraviolet-B receptor UVR8 (Q9FN03) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9FN03
Elsewhere: RCSB PDB 6XZM · PDBe 6XZM · UniProt Q9FN03

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