MolNFT v1 · #170057 · protein
Human SIRT6 3-318 in complex with ADP-ribose
6XV6: “Human SIRT6 3-318 in complex with ADP-ribose”. X-ray diffraction, 4 ligands (AR6, NCA, ZN). MolNFT v1 #170057 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6XV6
- Type
- protein
- Length
- 1,702 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q8N6T7
- Ligands
- AR6, NCA, ZN, SO4
Structure
x-ray diffraction · 6 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 288 | — | Q8N6T7 |
| B | — | protein | 279 | — | Q8N6T7 |
| C | — | protein | 287 | — | Q8N6T7 |
| D | — | protein | 280 | — | Q8N6T7 |
| E | — | protein | 279 | — | Q8N6T7 |
| F | — | protein | 289 | — | Q8N6T7 |
Ligands and binding sites
- AR6 · [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate · ligand · 6 copies · chains A, B, C, E, D, F
- NCA · Nicotinamide · ligand · 6 copies · chains A, B, C, D, E, F
- ZN · Zinc ion · metal · 6 copies · chains A, B, C, D, E, F
- SO4 · Sulfate ion · ion · 22 copies · chains A, F, B, C, E, D
- GOL · Glycerol · additive · 8 copies · chains A, B, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6XV6 · Human Sirt6 3-318 in complex with ADP-ribose · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8N6T7
- Elsewhere: RCSB PDB 6XV6 · PDBe 6XV6 · UniProt Q8N6T7
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