MolNFT v1 · #170048 · protein

Human myelin protein P2 mutant L27D

6XUW · Myelin P2 protein: “Human myelin protein P2 mutant L27D”. X-ray diffraction, 2 ligands (PLM, CL), 1 pocket (best druggability 0.84). MolNFT v1 #170048 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6XUW
Type: protein
Length: 133 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myelin P2 protein
UniProt: P02689
Ligands: PLM, CL
Pockets: 1 · best druggability 0.84

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 58% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myelin P2 protein	protein	133	15% helix, 58% strand	P02689

Ligands and binding sites

PLM · Palmitic acid · ligand · chains A
CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	308	0.84	0.94	37	PLM

Compared structures

6XUW · Human myelin protein P2 mutant L27D · the same entry in another collection · chain A against A, TM-score 1.00
P02689 · AlphaFold monomer V2.0 prediction for myelin P2 protein (P02689) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02689
Elsewhere: RCSB PDB 6XUW · PDBe 6XUW · UniProt P02689

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.