MolNFT v1 · #170018 · protein
Structure of dally-like protein in complex with O-palmitoleoyl serine
6XTZ · Dally-like, isoform a: “Structure of dally-like protein in complex with O-palmitoleoyl serine”. X-ray diffraction, 2 ligands (O18, NAG), 4 pockets (best druggability 0.80). MolNFT v1 #170018 on GenesisL1: 3D structure, binding sites…
- PDB
- 6XTZ
- Type
- protein
- Length
- 421 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dally-like, isoform a
- UniProt
- Q9VUG1
- Ligands
- O18, NAG
- Pockets
- 4 · best druggability 0.80
Structure
x-ray diffraction · 1 distinct chain · 68% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dally-like, isoform a | protein | 421 | 68% helix, 2% strand | Q9VUG1 |
Ligands and binding sites
- O18 · [(2~{S})-2-azanyl-3-oxidanylidene-propyl] (~{Z})-hexadec-9-enoate · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- GOL · Glycerol · additive · 4 copies · chains A
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 628 | 0.80 | 0.84 | 49 | O18, GOL |
| 2 | 81 | 0.57 | 0.87 | 17 | empty |
| 3 | 84 | 0.43 | 0.80 | 21 | empty |
| 4 | 118 | 0.40 | 0.75 | 21 | GOL |
Modifications
Observed in the structure: 7 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 6XTZ · Structure of Dally-like protein in complex with O-palmitoleoyl serine · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9VUG1
- Elsewhere: RCSB PDB 6XTZ · PDBe 6XTZ · UniProt Q9VUG1
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